Article
Deficit of HLA homozygotes in a Caucasian isolate.
Human immunology - 1 Jul 1993
Kostyu D D, Dawson D V, Elias S, Ober C
Abstract excerpt
Deficits of HLA-A, -B homozygotes observed many years ago in two inbred populations suggested negative selection against HLA homozygotes. To determine whether a similar deficiency would be observed in the S-leut Hutterites, a well-characterized Caucasian isolate of European ancestry, and to determine whether selection operated at the allele, locus, or haplotype level, observed and expected numbers of homozygotes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.