Article
Quantitative and qualitative variation of ETS-1 transcripts in hematologic malignancies.
Leukemia - 1 Nov 1993
Collyn d'Hooghe M, Galiègue-Zouitina S, Szymiczek D, Lantoine D, Quief S, Loucheux-Lefebvre M H, Kerckaert J P
Abstract excerpt
The ETS family proteins have a conserved DNA-binding domain and act as transcription factors. Three domains have been recently defined in human ETS-1 proteins and their role could depend upon the nature of alternative transcripts according to whether they possess or lack DNA binding and/or transcriptional activation domain and also point mutation that could affect these important domains. Expression of ETS-1 gene...
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