Article
Tay-Sachs disease--carrier screening, prenatal diagnosis, and the molecular era. An international perspective, 1970 to 1993. The International TSD Data Collection Network.
JAMA - 17 Nov 1993
Kaback M, Lim-Steele J, Dabholkar D, Brown D, Levy N, Zeiger K
Abstract excerpt
OBJECTIVES: To provide an update of the international experience with carrier screening and prenatal diagnosis for Tay-Sachs disease (TSD), to assess the impact of these efforts, and to review the recent developments in DNA technology with application to TSD carrier detection and screening. DESIG...
Topics
- Clinical Enzyme Tests
- Female
- Genetic Testing
- Global Health
- Heterozygote
- Humans
- Incidence
- International Cooperation
- Jews
- Male
- Mutation
- Pregnancy
- Prenatal Diagnosis
- Quality Control
- Tay-Sachs Disease
- beta-N-Acetylhexosaminidases