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Article

Evaluation of the risk for Tay-Sachs disease in individuals of French Canadian ancestry living in new England.

Clinical chemistry - 1 Mar 2007

Martin Dianna C, Mark Brian L, Triggs-Raine Barbara L, Natowicz Marvin R

Abstract excerpt

BACKGROUND: The assessment of risk for Tay-Sachs disease (TSD) in individuals of French Canadian background living in New England is an important health issue. In preliminary studies of the enzyme-defined carrier frequency for TSD among Franco-Americans in New England, we found frequencies (1:53) higher than predicted from the incidence of infantile TSD in this region. We have now further evaluated the risk for...

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PMID: 17259242
DOI: 10.1373/clinchem.2006.082727

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