Article
The ontogeny of estrogen receptors in heterochronic hippocampal and neocortical transplants demonstrates an intrinsic developmental program.
Brain research. Developmental brain research - 17 Sept 1993
O'Keefe J A, Pedersen E B, Castro A J, Handa R J
Abstract excerpt
We investigated the intrinsic vs. environmental regulation of estrogen receptor (ER) ontogeny in the neocortex, hippocampus and hypothalamus by employing a heterochronic transplantation paradigm. These studies were based on previous reports demonstrating that neural ER develop asynchronously with...
Topics
- Aging
- Animals
- Animals, Newborn
- Brain Tissue Transplantation
- Cerebral Cortex
- Estradiol
- Female
- Fetal Tissue Transplantation
- Frontal Lobe
- Hippocampus
- Neurons
- Phenotype
- Pregnancy
- Preoptic Area
- Rats
- Rats, Sprague-Dawley
- Receptors, Estrogen
- Transplantation, Heterotopic