Insulin as a predictor of coronary heart disease: interaction with apolipoprotein E phenotype. A report from the Multiple Risk Factor Intervention Trial.

doi:10.1016/1047-2797(94)90041-8

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Article

Insulin as a predictor of coronary heart disease: interaction with apolipoprotein E phenotype. A report from the Multiple Risk Factor Intervention Trial.

Annals of epidemiology - 1 Jan 1994

Orchard T J, Eichner J, Kuller L H, Becker D J, McCallum L M, Grandits G A

Abstract excerpt

The objective of this study was to examine whether fasting serum insulin is a predictor of coronary heart disease in high-risk US men, and whether any such predictive role explains the enhanced cardiovascular risk seen in subjects with the apolipoprotein (Apo) E 3/2 phenotype. This was a nested c...

Topics

Adult
Apolipoprotein E2
Apolipoprotein E3
Apolipoprotein E4
Apolipoproteins E
Case-Control Studies
Cholesterol, LDL
Coronary Disease
Fasting
Humans
Insulin
Logistic Models
Male
Matched-Pair Analysis
Middle Aged
Myocardial Infarction
Phenotype
Predictive Value of Tests

Source

Open in PubMed

Identifiers

PMID: 8205270
DOI: 10.1016/1047-2797(94)90041-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8205270-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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