Expression and evolution of members of the Trypanosoma cruzi trypomastigote surface antigen multigene family.

doi:10.1016/0166-6851(94)90013-2

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Article

Expression and evolution of members of the Trypanosoma cruzi trypomastigote surface antigen multigene family.

Molecular and biochemical parasitology - 1 Jan 1994

Ruef B J, Dawson B D, Tewari D, Fouts D L, Manning J E

Abstract excerpt

The trypomastigote specific surface antigens of Trypanosoma cruzi are encoded by a supergene family which includes the TSA family. The TSA family is characterized by the presence of a 27-bp tandem repeat array in the coding region. Here, we report the characterization and analysis of the three TSA family members in the Esmeraldo strain of the parasite. In this strain 2 distinct telomeric members are expressed...

Topics

Amino Acid Sequence
Animals
Antigens, Protozoan
Antigens, Surface
Base Sequence
Biological Evolution
DNA, Protozoan
Gene Conversion
Gene Expression
Genes, Protozoan
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Multigene Family

Repetitive Sequences, Nucleic Acid

Restriction Mapping

Sequence Homology, Amino Acid

Sequence Homology, Nucleic Acid

Trypanosoma cruzi

Source

Open in PubMed

Identifiers

PMID: 8183309
DOI: 10.1016/0166-6851(94)90013-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8183309-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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