Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions.

doi:10.1099/0022-1317-75-5-1053

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Article

Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions.

The Journal of general virology - 1 May 1994

Simmonds P, Smith D B, McOmish F, Yap P L, Kolberg J, Urdea M S, Holmes E C

Abstract excerpt

Isolates of hepatitis C virus (HCV) show considerable nucleotide sequence variability throughout the genome. Comparisons of complete genome sequences have been used as the basis of classification of HCV into a number of genotypes that show 67 to 77% sequence similarity. In order to investigate wh...

Topics

Base Sequence
Biological Evolution
Genotype
Hepacivirus
Molecular Sequence Data
Phylogeny
Sequence Homology, Nucleic Acid
Viral Envelope Proteins
Viral Nonstructural Proteins

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