Article
Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions.
The Journal of general virology - 1 May 1994
Simmonds P, Smith D B, McOmish F, Yap P L, Kolberg J, Urdea M S, Holmes E C
Abstract excerpt
Isolates of hepatitis C virus (HCV) show considerable nucleotide sequence variability throughout the genome. Comparisons of complete genome sequences have been used as the basis of classification of HCV into a number of genotypes that show 67 to 77% sequence similarity. In order to investigate whether sequence relationships between genotypes are equivalent in different regions of the genome, we have carried out...
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