Article
Genetic polymorphism of factor B (Bf) and C3 component of complement in type 1 (insulin-dependent) diabetes mellitus: BFQO allele observed in a diabetic child.
Folia biologica - 1 Jan 1993
Staneková D, Niks M, Buc M, Starsia Z, Michalková
Abstract excerpt
C3 and Bf polymorphisms were studied in 215 and 192 children with type 1 diabetes mellitus (IDDM), respectively. No significant differences in C3 phenotypes and allele frequencies were found between IDDM patients and a healthy population. The rare allele BfF1 was found in 9.37% of diabetic patients but in only 0.35% of the general Slovak population (0.0468 vs. 0.0017). An increased frequency rate of BfSO.7 was...
Topics
- Adolescent
- Alleles
- Child
- Child, Preschool
- Complement C3
- Complement Factor B
- Diabetes Mellitus, Type 1
- Female
- Gene Frequency
- Genotype
- Humans