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Article

An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome

1 Jan 1993

Abstract excerpt

ICF syndrome has been described as the association of variable immunodeficiency, facial anomalies and centromeric heterochromatin instability. Since the chromosome rearrangements seen in cells of ICF patients are reminiscent of the chromosomal changes induced by the undermethylating agent 5-azacytidine in the late S-phase, we have analyzed the methylation pattern of satellite sequences in four patients. These...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8102570
DOI: 10.1093/hmg/2.6.731

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