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Article

Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells.

Human molecular genetics - 1 Sept 2002

Tao Qian, Huang He, Geiman Theresa M, Lim Chai Yen, Fu Li, Qiu Guo-Hua, Robertson Keith D

Abstract excerpt

ICF syndrome (immunodeficiency, centromere instability and facial anomalies) is a recessive human genetic disorder resulting from mutations in the DNA methyltransferase 3B (DNMT3B) gene. Patients with this disease exhibit numerous chromosomal abnormalities, including anomalous decondensation, pai...

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Source

Identifiers

PMID: 12189161
DOI: 10.1093/hmg/11.18.2091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12189161-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells.PMID 12189161Read ↗

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