Integrated clinical and basic studies related to circumventing non-small cell lung cancer drug resistance.

doi:10.1016/0169-5002(94)91669-1

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Article

Integrated clinical and basic studies related to circumventing non-small cell lung cancer drug resistance.

Lung cancer (Amsterdam, Netherlands) - 1 Mar 1994

Mulshine J L, Johnson B E, Gazdar A F, Shaw G L, Kramer B S, Mitsudomi T, Minna J D, Pass H, Phelps R, Ghosh B

Abstract excerpt

Consideration of a range of clinical and basic studies conducted at the National Cancer Institute which explore the nature of the tumor biology of lung identify the limitations of using chemotherapy for the treatment of advanced lung cancer. No single mechanistic explanation for lung cancer's che...

Topics

Antineoplastic Agents
Antineoplastic Combined Chemotherapy Protocols
Carboplatin
Carcinoma, Non-Small-Cell Lung
Chemotherapy, Adjuvant
Cisplatin
Clinical Trials, Phase II as Topic
Combined Modality Therapy
Drug Resistance
Etoposide

Humans

Isotretinoin

Lung Neoplasms

Neoplasms, Second Primary

Neoplastic Stem Cells

Oncogenes

Phenotype

Tumor Cells, Cultured

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