Article
Assessment of Sperm Chromatin Condensation: An Important Test for Prediction of IVF Outcome
1 Jan 1994
Abstract excerpt
Regular condensation of sperm chromatin during spermiogenesis, which allows decondensation after penetration of the oocyte, is a prerequisite for successful fertilization. During spermiogenesis particular nucleoproteins (histones) are normally replaced by different proteins (protamines). In the case of disturbed chromatin condensation the histones persist, which can be demonstrated by aniline blue staining. This...
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