Segregation analysis of Alagille syndrome.

doi:10.1136/jmg.31.6.453

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Article

Segregation analysis of Alagille syndrome.

Journal of medical genetics - 1 Jun 1994

Dhorne-Pollet S, Deleuze J F, Hadchouel M, Bonaïti-Pellié C

Abstract excerpt

Alagille syndrome (AGS) is a well defined genetic disorder characterised by five major features. An autosomal dominant mode of transmission with reduced penetrance has been suggested by the analysis of a limited number of families. However there has been no statistical analysis. We report here th...

Topics

Alagille Syndrome
Child
Chromosomes, Human, Pair 20
Female
Gene Expression
Genes, Dominant
Genetic Techniques
Genotype
Humans
Male
Models, Genetic
Pedigree
Phenotype
Probability

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