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Article

Experimental reproduction of the papilloma-carcinoma complex of the alimentary canal in cattle

1 Jan 1994

Abstract excerpt

Bovine papillomavirus type 4 (BPV-4) is the aetiological agent of epithelial papillomas of the upper alimentary canal in cattle. These benign tumours can become a focus for transformation to squamous cell carcinomas in animals feeding on bracken fern. Strong epidemiological evidence suggests that the progression to malignancy is due to the interplay between BPV-4 and mutagenic and immunosuppressing chemicals...

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PMID: 8055638
DOI: 10.1093/carcin/15.8.1597

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