Article
Altered expression of epidermal growth factor receptor and estrogen receptor in MCF-7 cells after single and repeated radiation exposures.
International journal of radiation oncology, biology, physics - 1 Jul 1994
Schmidt-Ullrich R K, Valerie K C, Chan W, McWilliams D
Abstract excerpt
PURPOSE: Studies on radiation-induced changes in gene expression are likely to be very important in developing a better understanding of cellular responses to ionizing radiation. While there is some information on the activation of cellular signal transduction pathways after radiation, few late r...
Topics
- Breast Neoplasms
- Cell Cycle
- Cell Survival
- Dose-Response Relationship, Radiation
- ErbB Receptors
- Gene Expression
- Gene Expression Regulation, Neoplastic
- Humans
- Phenotype
- RNA, Messenger
- Receptors, Estrogen
- Transforming Growth Factor alpha
- Tumor Cells, Cultured
- Up-Regulation