Genetic variability of the emm-related gene of the large vir regulon of group A streptococci: potential intra- and intergenomic recombination events.

doi:10.1007/BF00279579

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Article

Genetic variability of the emm-related gene of the large vir regulon of group A streptococci: potential intra- and intergenomic recombination events.

Molecular & general genetics : MGG - 15 Jun 1994

Podbielski A, Krebs B, Kaufhold A

Abstract excerpt

One of the most prevalent genetic lineages of group A streptococci (GAS) harbors a genomic locus termed the large vir regulon, which contains an emm gene encoding the antiphagocytic M protein, and structurally related fcrA and enn (emm-related) genes encoding immunoglobulin-binding proteins. In the present study more than 100 large vir regulons from 42 different GAS serotypes were analyzed by PCR and partial DNA...

Topics

Amino Acid Sequence
Antigens, Bacterial
Bacterial Outer Membrane Proteins
Bacterial Proteins
Base Sequence
Carrier Proteins
Genes, Bacterial
Genetic Variation
Molecular Sequence Data
Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Regulon

Sequence Deletion

Sequence Homology, Nucleic Acid

Serotyping

Streptococcus pyogenes

Virulence

Source

Open in PubMed

Identifiers

PMID: 8028586
DOI: 10.1007/BF00279579

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8028586-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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