Article
Pseudohypoaldosteronism: molecular characterization of the mineralocorticoid receptor.
The Journal of clinical endocrinology and metabolism - 1 Jul 1994
Komesaroff P A, Verity K, Fuller P J
Abstract excerpt
Mineralocorticoid resistance (pseudohypoaldosteronism) is a rare condition first described in 1958 and associated with failure to thrive, salt wasting, and dehydration in infancy. In the index case it has previously been shown that binding of aldosterone to mineralocorticoid receptors in peripher...
Topics
- Base Sequence
- Blotting, Southern
- Cloning, Molecular
- DNA
- DNA Probes
- Drug Resistance
- Humans
- Infant
- Male
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- Polymerase Chain Reaction