Article
Adrenocortical dysplasia: a mouse model system for adrenocortical insufficiency.
The Journal of endocrinology - 1 Apr 1994
Beamer W G, Sweet H O, Bronson R T, Shire J G, Orth D N, Davisson M T
Abstract excerpt
A spontaneous autosomal recessive mutation causing disordered morphogenesis of the adrenal cortex has been identified in DW/J inbred strain mice and named adrenocortical dysplasia (acd). The acd mutant gene has been mapped just proximal to oligosyndactyly (Os) and esterase-1 (Es-1) in the central...
Topics
- Adrenal Cortex
- Adrenal Insufficiency
- Animals
- Chromosome Mapping
- Disease Models, Animal
- Female
- Genes, Recessive
- Homozygote
- Hydronephrosis
- Male
- Mice
- Mice, Mutant Strains
- Microscopy, Electron
- Phenotype