Okadaic acid promotes cell division in synchronized Tetrahymena pyriformis and in the cell division-arrested (cdaA1) temperature-sensitive mutant of T. thermophila.

Abstract excerpt

1. Okadaic acid (OA) at 0.5 to 1 microM accelerated the onset and completion of division in heat-synchronized Tetrahymena pyriformis, especially where cells had been transiently delayed in the presence of dimethyl sulfoxide (DMSO). 2. The cell division-arrested mutant, cdaA1, of Tetrahymena thermophila ceased dividing after being shifted from the permissive temperature of 22 degrees C to the restrictive...

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