Article
Characterization of a variant glucose-6-phosphate dehydrogenase from the south Indian population.
Indian journal of biochemistry & biophysics - 1 Aug 1994
Ramadevi R, Savithri H S, Bittles A H, Rao N A
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) is coded by a gene on the X-chromosome. Earlier studies have shown that the South Indian population has a high incidence of this enzyme deficiency. The electrophoretic mobility, pH optimum and the Km values for G6PD from normal and variant individuals were identical. However, the specific activity of the variant enzyme was 8 times less compared to the value of the normal...
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