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Article

Physical mapping of the split hand/split foot locus on chromosome 7 and implication in syndromic ectrodactyly

1 Jan 1994

Abstract excerpt

Split hand/split foot (ectrodactyly; SHSF) is a human developmental malformation characterized by missing digits and claw-like extremities. An autosomal dominant form of this disorder has been mapped to 7q21.3-q22.1; the locus has been designated SHFD1. We have constructed a physical map consisting of overlapping yeast artificial chromosome clones for the entire region. Somatic cell hybrid and fluorescent in situ...

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Congenital limb and hand anomalies
Genomics and Chromatin Dynamics
Prenatal Screening and Diagnostics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 7987313
DOI: 10.1093/hmg/3.8.1345

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Physical mapping of the split hand/split foot locus on chromosome 7 and implication in syndromic ectrodactylyPMID 7987313Read ↗

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