Birth defects: from molecules to mechanisms.

Abstract excerpt

Birth defects remain a major clinical problem and, although much progress has been made in prenatal diagnosis, few measures are available for primary prevention. This is due, in large part, to our rudimentary understanding of the embryonic mechanisms of birth defects. Until recently it was customary to concentrate on defining teratogenic factors that may be active in humans. Now, with the rapid expansion in...

Topics

• Animals
• Cloning, Molecular
• Congenital Abnormalities
• Embryonic and Fetal Development
• Female
• Humans
• In Vitro Techniques
• Infant, Newborn
• Mice
• Models, Genetic
• Mutation
• Pregnancy