Effects on Bacillus subtilis of a conditional lethal mutation in the essential GTP-binding protein Obg.

doi:10.1128/jb.176.23.7155-7160.1994

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Article

Effects on Bacillus subtilis of a conditional lethal mutation in the essential GTP-binding protein Obg.

Journal of bacteriology - 1 Dec 1994

Kok J, Trach K A, Hoch J A

Abstract excerpt

The obg gene is part of the spo0B sporulation operon and codes for a GTP-binding protein which is essential for growth. A temperature-sensitive mutant in the obg gene was isolated and found to be the result of two closely linked missense mutations in the amino domain of Obg. Temperature shift experiments revealed that the mutant was able to continue cell division for 2 to 3 generations at the nonpermissive...

Topics

Amino Acid Sequence
Bacillus subtilis
Bacterial Proteins
Base Sequence
Cloning, Molecular
Crossing Over, Genetic
GTP-Binding Proteins
Genes, Bacterial
Genes, Lethal
Hot Temperature
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Operon

Recombination, Genetic

Restriction Mapping

Sigma Factor

Spores, Bacterial

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 7961486
DOI: 10.1128/jb.176.23.7155-7160.1994
PMCID: PMC197102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7961486-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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