Article
Characteristics of the transmission of the FMR1 gene from carrier females in a prospective sample of conceptuses.
American journal of medical genetics - 15 Jul 1994
Sherman S L, Maddalena A, Howard-Peebles P N, Brown W T, Nolin S, Jenkins E, Schwartz C, Tarrelton J, Shapiro L R, Smits A P
Abstract excerpt
The Prospective Study of the Fragile X Syndrome is a large collaborative effort designed to collect prospective data on the pregnancy outcomes of individuals who carry the fragile X mutation. The goal of this 5-year study is to obtain empiric recurrence risks and population parameters for the fra...
Topics
- Female
- Fragile X Syndrome
- Gene Dosage
- Gene Expression
- Heterozygote
- Humans
- Mutation
- Predictive Value of Tests
- Pregnancy
- Pregnancy Outcome
- Prospective Studies
- Recurrence
- Repetitive Sequences, Nucleic Acid
- Risk Assessment