Article
Phenotypic and functional modulation of normal human alveolar macrophages by histamine.
American journal of respiratory cell and molecular biology - 1 Oct 1994
Vignola A M, Chanez P, Paul-Lacoste P, Paul-Eugène N, Godard P, Bousquet J
Abstract excerpt
Alveolar macrophages (AM) play a regulatory role in asthma. AM from asthmatics are activated, release increased amounts of cytokines, and express higher levels of the low affinity receptor for IgE (Fc epsilon RIIb/CD23b) and receptors for adhesion molecules. The bronchial microenvironment may modulate the phenotypic and functional characteristics of AM. On AM from normal subjects, the effects of histamine were...
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