Article
Quantitative trait loci underlying gene product variation: a novel perspective for analyzing regulation of genome expression.
Genetics - 1 May 1994
Damerval C, Maurice A, Josse J M, de Vienne D
Abstract excerpt
A methodology to dissect the genetic architecture of quantitative variation of numerous gene products simultaneously is proposed. For each individual of a segregating progeny, proteins extracted from a given organ are separated using two-dimensional electrophoresis, and their amounts are estimated with a computer-assisted system for spot quantification. Provided a complete genetic map is available, statistical...
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