Lack of RH C/E expression in the Rhesus D--phenotype is the result of a gene deletion.

doi:10.1111/j.1469-1809.1994.tb00722.x

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Article

Lack of RH C/E expression in the Rhesus D--phenotype is the result of a gene deletion.

Annals of human genetics - 1 Jan 1994

Blunt T, Steers F, Daniels G, Carritt B

Abstract excerpt

We have investigated the arrangement of genes in the rare Rh (Rhesus) partial null condition D--. Southern blot and PCR studies under conditions which distinguish the highly homologous RH D and RH C/E genes show that in an Icelandic family with the D-- haplotype at least 85% of the RH C/E gene is...

Topics

Base Sequence
Exons
Gene Deletion
Heterozygote
Homozygote
Humans
Iceland
Introns
Molecular Sequence Data
Phenotype
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Rh-Hr Blood-Group System

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