Article
Physical and genetic mapping of the serpin gene cluster at 14q32.1: allelic association and a unique haplotype associated with alpha 1-antitrypsin deficiency.
American journal of human genetics - 1 Jul 1994
Byth B C, Billingsley G D, Cox D W
Abstract excerpt
The alpha 1-antitrypsin (PI) gene is part of a cluster of structurally related serine protease inhibitor genes localized at chromosome 14q32.1, a cluster that includes the alpha 1-antichymotrypsin (AACT), protein C inhibitor (PCI), and corticosteroid-binding globulin (CBG) genes and the alpha 1-a...
Topics
- Alleles
- Base Sequence
- Chi-Square Distribution
- Chromosome Mapping
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 14
- DNA Primers
- Genetic Linkage
- Haplotypes
- Humans
- Lod Score
- Molecular Sequence Data
- Multigene Family
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Repetitive Sequences, Nucleic Acid
- Serine Proteinase Inhibitors
- alpha 1-Antitrypsin