Article
Molecular diagnosis of cystic fibrosis in Maritime Canada.
Clinical and investigative medicine. Medecine clinique et experimentale - 1 Feb 1994
Corsten P G, Blight C E, Riddell D C, Hamilton D C, Cole D E
Abstract excerpt
Many of the people in Maritime Canada can trace their ancestry to some of the oldest settlements in North America. Consequently, both founder effect and genetic drift can be shown to account for the high frequency of some genetic disorders and virtual absence of others. The birth prevalence rate for cystic fibrosis (CF) in Maritime Canada is similar to other North American regions, but we recognized that similar...
Topics
- Cystic Fibrosis
- Female
- Gene Deletion
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Male
- Mutation
- Nova Scotia
- Polymorphism, Restriction Fragment Length