Article
Cystic fibrosis in the southern Midwest United States: molecular characterization of the common mutations.
The American journal of the medical sciences - 1 Feb 1994
Hoffman R A, Floyd M E, Whetsell L H, Kramer J C, Schaefer F V
Abstract excerpt
The identification of different mutations that cause cystic fibrosis in the people of Kansas and Oklahoma has been performed by examining 124 independent cystic fibrosis genes for the 14 most commonly mutated loci. The delta F508 3bp deletion represented 79% of the alleles, and 7% of the remaining alleles were found to harbor the mutations of R553X, G542X, or G551D. None of the remaining 10 common mutations were...
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