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Article

Radiation-induced Genomic Instability: Delayed Cytogenetic Aberrations and Apoptosis in Primary Human Bone Marrow Cells

1 Jan 1995

Abstract excerpt

Transmissible chromosomal instability, characterized by non-clonal cytogenetic aberrations with a high frequency of chromatid-type aberrations together with a lower frequency of chromosome-type aberrations, has been demonstrated in the clonal descendants of human haemopoietic stem cells after alpha- but not X-irradiation. Comparable cytogenetic abnormalities have also been demonstrated in non-clonal cultures of...

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PMID: 7897277
DOI: 10.1080/09553009514550341

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