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High correlation between Chagas' disease serology and PCR-based detection ofTrypanosoma cruzikinetoplast DNA in Bolivian children living in an endemic area

1 Dec 1994

Abstract excerpt

The detection of Trypanosoma cruzi kinetoplast DNA by polymerase chain reaction (PCR) amplification is a potentially powerful tool for the parasitological diagnosis of Chagas' disease. We have applied this technique in a field situation in Bolivia, where 45 children from a primary school were subjected to serological testing, buffy coat analysis and PCR diagnosis. 26 of the 28 serology-positive individuals were...

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PMID: 7851750
DOI: 10.1111/j.1574-6968.1994.tb07318.x

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