Immunohistochemical localization of interferon-gamma in normal human ovary.

doi:10.3109/09513599409072450

Article

Immunohistochemical localization of interferon-gamma in normal human ovary.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Sept 1994

Grasso G, Asano A, Minagawa T, Tanaka T, Fujimoto S, Muscettola M

Abstract excerpt

There is increasing evidence that cytokines are important intraovarian non-steroidal regulators. The aim of the present study was to evaluate the presence in the human ovary of interferon (IFN)-gamma, a cytokine produced by T lymphocytes after mitogenic or antigenic stimulation. Very low levels of IFN-gamma (0.025-0.057 IU/ml) were found in follicular fluid of large spontaneously maturing follicles, in the...

Topics

Adult
Antibodies, Monoclonal
CD8 Antigens
Female
Follicular Fluid
HLA-DR Antigens
Humans
Immunohistochemistry
Interferon-gamma
Ovary
Phenotype

T-Lymphocytes, Helper-Inducer

T-Lymphocytes, Regulatory

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