Localization of a gene for autosomal dominant amelogenesis imperfecta (ADAI) to chromosome 4q.

doi:10.1093/hmg/3.9.1621

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Article

Localization of a gene for autosomal dominant amelogenesis imperfecta (ADAI) to chromosome 4q.

Human molecular genetics - 1 Sept 1994

Forsman K, Lind L, Bäckman B, Westermark E, Holmgren G

Abstract excerpt

Amelogenesis imperfecta (AI), is an inherited odontological disease which affects the formation of enamel. We report a linkage analysis study performed on three Swedish families, where the affected members had an autosomal dominant variant of AI (ADAI) clinically characterized as local hypoplasti...

Topics

Amelogenesis Imperfecta
Chromosome Mapping
Chromosomes, Human, Pair 4
DNA, Satellite
Dental Enamel Hypoplasia
Female
Genes, Dominant
Genetic Linkage
Genetic Markers
Humans
Lod Score
Male
Pedigree
Phenotype
Recombination, Genetic
Sweden

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