Article
The validation of short tandem repeat (STR) loci for use in forensic casework.
International journal of legal medicine - 1 Jan 1994
Lygo J E, Johnson P E, Holdaway D J, Woodroffe S, Whitaker J P, Clayton T M, Kimpton C P, Gill P
Abstract excerpt
A quadruplex reaction has been developed which amplifies the short tandem repeat (STR) loci HUM-VWA31/A, HUMTHO1, HUMF13A1 and HUMFES/FPS. Detection of the PCR products employs denaturing polyacrylamide gels coupled with fluorescent-based technology. This system has been evaluated for use in routine forensic casework and has been shown to be both robust and reproducible. The quadruplex reaction is as sensitive as...
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