Biochemical characterization of four new erythrocyte pyruvate kinase variants.

doi:10.1159/000204184

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Article

Biochemical characterization of four new erythrocyte pyruvate kinase variants.

Acta haematologica - 1 Jan 1994

Tegos C, Anagnostoulis G

Abstract excerpt

Pyruvate kinase (PK) from four patients with moderate to severe congenital non-spherocytic haemolytic anaemia was characterized by methods recommended by the ICSH. The possibility that two of the patients are true homozygotes cannot be ruled out, while the other two apparently represent double he...

Topics

Adolescent
Allosteric Regulation
Anemia, Hemolytic, Congenital Nonspherocytic
Child, Preschool
Erythrocytes
Female
Genetic Variation
Greece
Heterozygote
Homozygote
Humans
Infant
Male
Pedigree
Pyruvate Kinase

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