Article
One of the two common mutations causing factor XI deficiency in Ashkenazi Jews (type II) is also prevalent in Iraqi Jews, who represent the ancient gene pool of Jews.
Blood - 15 Jan 1995
Shpilberg O, Peretz H, Zivelin A, Yatuv R, Chetrit A, Kulka T, Stern C, Weiss E, Seligsohn U
Abstract excerpt
In recent years four mutations causing factor XI deficiency have been identified in Jews of Ashkenazi (European) origin. Two of them, type II (a nonsense mutation) and type III (a missense mutation), were found to prevail among 125 unrelated Ashkenazi Jews with severe factor XI deficiency. A find...
Topics
- Aged
- Aged, 80 and over
- Europe
- Factor XI
- Factor XI Deficiency
- Female
- Gene Frequency
- Gene Pool
- Genetic Testing
- Genotype
- History, Modern 1601-
- Humans
- Inpatients
- Iraq
- Israel
- Jews
- Male
- Middle Aged