Article
Gene sequence and biochemical characterization of FOX-1 from Klebsiella pneumoniae, a new AmpC-type plasmid-mediated beta-lactamase with two molecular variants.
Antimicrobial agents and chemotherapy - 1 Sept 1994
Gonzalez Leiza M, Perez-Diaz J C, Ayala J, Casellas J M, Martinez-Beltran J, Bush K, Baquero F
Abstract excerpt
Klebsiella pneumoniae BA32, a clinical isolate from Buenos Aires, Argentina, was found to produce a plasmid-encoded beta-lactamase (FOX-1) which conferred resistance to broad-spectrum cephalosporins and cephamycins. Resistance could be transferred by conjugation or transformation into Escherichia...
Topics
- Aged
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cloning, Molecular
- Conjugation, Genetic
- DNA, Bacterial
- Drug Resistance, Microbial
- Genes, Bacterial
- Genetic Variation
- Humans
- Isoenzymes
- Klebsiella pneumoniae
- Molecular Sequence Data