Article
Adaptive mutation and cocolonization during Helicobacter pylori infection of gnotobiotic piglets.
Infection and immunity - 1 Jan 1995
Akopyants N S, Eaton K A, Berg D E
Abstract excerpt
Clinical isolates of Helicobacter pylori, the gastric pathogen implicated in gastritis, peptic ulcers, and gastric cancer in humans, are diverse in traits likely to be important for colonization and disease. Here we report studies using a gnotobiotic piglet-H. pylori infection model to test for h...
Topics
- Adaptation, Biological
- Animals
- Base Sequence
- DNA Fingerprinting
- Gastric Mucosa
- Genome, Bacterial
- Germ-Free Life
- Helicobacter Infections
- Helicobacter pylori
- Molecular Sequence Data
- Mutation
- Species Specificity