Article
Two craniosynostotic syndrome loci, Crouzon and Jackson-Weiss, map to chromosome 10q23-q26.
Genomics - 15 Jul 1994
Li X, Lewanda A F, Eluma F, Jerald H, Choi H, Alozie I, Proukakis C, Talbot C C, Vander Kolk C, Bird L M
Abstract excerpt
Crouzon syndrome (MIM 123500) is a common autosomal dominant form of craniosynostosis with shallow orbits, ocular proptosis, and maxillary hypoplasia. Jackson-Weiss syndrome (MIM 123150) is another autosomal dominant craniosynostosis with highly variable phenotypic expression. Unlike Crouzon syndrome, Jackson-Weiss syndrome is associated with foot anomalies. We performed two point linkage and haplotype analyses...
Topics
- Abnormalities, Multiple
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- Craniofacial Dysostosis
- Craniosynostoses
- Ethnicity
- Female
- Foot Deformities, Congenital
- Genetic Markers
- Haplotypes
- Humans