Extent and kinetics of genetic change in the omp1 gene of Chlamydia trachomatis in two villages with endemic trachoma.

doi:10.1093/infdis/172.1.268

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Article

Extent and kinetics of genetic change in the omp1 gene of Chlamydia trachomatis in two villages with endemic trachoma.

The Journal of infectious diseases - 1 Jul 1995

Hayes L J, Pecharatana S, Bailey R L, Hampton T J, Pickett M A, Mabey D C, Watt P J, Ward M E

Abstract excerpt

Variants of Chlamydia trachomatis in two Gambian villages with hyperendemic trachoma were analyzed by omp1-based polymerase chain reaction and sequencing from conjunctival swabs. Samples collected over a 22-month period included a complete cross-sectional study of each village. Overall, 4 genovar A and 4 B variants were characterized by point mutations in the omp1 gene, resulting in changes in the inferred amino...

Topics

Amino Acid Sequence
Bacterial Outer Membrane Proteins
Base Sequence
Chlamydia trachomatis
Conjunctiva
Cross-Sectional Studies
DNA Primers
Gambia
Genes, Bacterial
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Kinetics

Molecular Sequence Data

Polymerase Chain Reaction

Porins

Sequence Homology, Amino Acid

Trachoma

Source

Open in PubMed

Identifiers

PMID: 7797929
DOI: 10.1093/infdis/172.1.268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7797929-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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