Article
High incidence of cystic fibrosis on the Faroe Islands: a molecular and genealogical study.
Human genetics - 1 Jun 1995
Schwartz M, Sørensen N, Brandt N J, Høgdall E, Holm T
Abstract excerpt
We have studied the genetics of cystic fibrosis (CF) in The Faroe Islands. Based on the number of affected children born during the period 1954-1993, the incidence of CF at birth is 1:1775, which is more than twice the incidence in the rest of Denmark. We have tested all known CF patients and/or their parents for the presence of delta F508 and found it to be the only CF mutation in this population. Based on...
Topics
- Cystic Fibrosis
- Denmark
- Female
- Founder Effect
- Haplotypes
- Humans
- Incidence
- Infant, Newborn
- Mutation
- Pedigree
- Polymorphism, Restriction Fragment Length
- Pregnancy