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Article

Polymorphism and peripheral levels of apolipoprotein(a) in polygenic hypercholesterolemia and combined hyperlipidemia.

Clinical and investigative medicine. Medecine clinique et experimentale - 1 Feb 1995

Shen G X, Mymin D, Dembinski T, Krahn A, Angel A

Abstract excerpt

This study demonstrates that peripheral apolipoprotein(a) [apo(a)] levels are higher in patients with polygenic hypercholesterolemia (PH) and combined hyperlipidemia (CH) than in controls. Levels of apo(a) inversely correlate with apo(a) isoform sizes. For a given apo(a) isoform, apo(a) levels are higher in PH and CH patients. Higher frequencies of smaller apo(a) isoforms were found in PH and CH patients than in...

Read the complete abstract on PubMed

Topics

Adult
Aged
Apolipoproteins
Apoprotein(a)
Coronary Disease
Female
Humans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Hypercholesterolemia

Hyperlipidemia, Familial Combined

Immunoblotting

Lipoprotein(a)

Male

Middle Aged

Phenotype

Polymorphism, Genetic

Source

Identifiers

PMID: 7768064

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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