Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diagnosis of "sporadic" Huntington's disease.

Journal of the neurological sciences - 1 Mar 1995

Dürr A, Dodé C, Hahn V, Pêcheux C, Pillon B, Feingold J, Kaplan J C, Agid Y, Brice A

Abstract excerpt

The diagnosis of Huntington's disease (HD) in patients with progressive chorea and mental impairment, but without similarly affected relatives, remains uncertain and impedes genetic counseling. Twenty patients with suspected HD, but with no family history of the disease underwent molecular analysis of the CAG repeat in the IT15 gene for HD. Eighteen patients displayed the HD expanded allele and two had CAG...

Topics

Adult
Aged
Alleles
Base Sequence
Female
Humans
Huntington Disease
Male
Middle Aged
Neuropsychological Tests
Repetitive Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7751845
DOI: 10.1016/0022-510x(94)00250-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7751845-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diagnosis of "sporadic" Huntington's disease.PMID 7751845Read ↗

Molecular analysis of the IT15 gene in patients with apparently 'sporadic' Huntington's disease.Semantic proximity Read ↗

Molecular diagnosis of Huntington disease in Brazilian patients.Semantic proximity Read ↗

The Huntington's disease-like syndromes: what to consider in patients with a negative Huntington's disease gene test.Semantic proximity Read ↗

Huntington's disease CAG trinucleotide repeats in pathologically confirmed post-mortem brains.Semantic proximity Read ↗

Diagnostic genetic testing for Huntington's diseaseSemantic proximity Read ↗

Psychopathology in Verified Huntington’s Disease Gene CarriersSemantic proximity Read ↗

Genetically confirmed clinical Huntington's disease with no observable cell loss.Semantic proximity Read ↗

Maternal transmission in sporadic Huntington's disease.Semantic proximity Read ↗

Identification of an expanded CAG repeat in the Huntington's disease gene (IT15) in a family reported to have benign hereditary chorea.Semantic proximity Read ↗

DNA testing for Huntington disease in the Turkish population.Semantic proximity Read ↗

Psychiatric symptoms and CAG expansion in Huntington's diseaseSemantic proximity Read ↗

Cognitive changes in asymptomatic carriers of the Huntington disease mutation gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.