Present and future of rapid and/or high-throughput methods for nucleic acid testing.

doi:10.1016/j.cccn.2005.07.009

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Article

Present and future of rapid and/or high-throughput methods for nucleic acid testing.

Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2006

Csako Gyorgy

Abstract excerpt

BACKGROUND: Behind the success of 'completing' the human genome project was a more than 30-year history of technical innovations for nucleic acid testing. METHODS: Discovery of specific restriction endonucleases and reverse transcriptase was followed shortly by the development of the first diagnostic nucleic acid tests in the early 1970s. Introduction of Southern, Northern and dot blotting and DNA sequencing...

Topics

Animals
Gene Expression Profiling
Genetic Techniques
Genotype
Humans
Molecular Diagnostic Techniques
Nucleic Acid Amplification Techniques
Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Sensitivity and Specificity

Source

Open in PubMed

Identifiers

PMID: 16102738
DOI: 10.1016/j.cccn.2005.07.009

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