Article
Analysis of CFTR transcripts in nasal epithelial cells and lymphoblasts of a cystic fibrosis patient with 621 + 1G-->T and 711 + 1G-->T mutations.
Human molecular genetics - 1 Jun 1993
Zielenski J, Bozon D, Markiewicz D, Aubin G, Simard F, Rommens J M, Tsui L C
Abstract excerpt
We have analyzed the CFTR mRNA populations in a cystic fibrosis patient heterozygous for the 621 + 1G-->T and 711 + 1G-->T mutations. Total RNA isolated from the nasal epithelial cells and Epstein-Barr virus-transformed lymphoblasts derived from this patient was reversely transcribed and a region...
Topics
- Alleles
- B-Lymphocytes
- Base Sequence
- Cell Line, Transformed
- Cells, Cultured
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Epithelium
- Exons
- Herpesvirus 4, Human
- Heterozygote
- Membrane Proteins
- Molecular Sequence Data
- Nasal Mucosa
- Nasal Polyps