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Article

Effect of D-penicillamine on the T cell phenotype in scleroderma. Comparison between treated and untreated patients.

Clinical and experimental rheumatology - 1 Jan 2000

Rosada M, Fiocco U, De Silvestro G, Doria A, Cozzi L, Favaretto M, Todesco S

Abstract excerpt

To investigate the possible immunomodulatory mechanism of D-penicillamine in Scleroderma (Scl), we analysed the surface phenotype of circulating T lymphocytes in 17 Scl patients, 6 of these studied before and after D-penicillamine treatment, 8 only before and 3 only after treatment. The drug was administered for 6 to 24 consecutive months with a median daily dose of 500 mg. The study of peripheral blood purified...

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Identifiers

PMID: 7685256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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