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Article

Alternative splicing in the first nucleotide binding fold of CFTR.

Human molecular genetics - 1 Mar 1993

Will K, Stuhrmann M, Dean M, Schmidtke J

Abstract excerpt

CFTR mRNA transcripts were analyzed from freshly isolated nasal epithelial cells and lymphocytes (six individuals) and from lymphocytes alone from 14 further individuals. In four of these 20 individuals alternative splicing was observed within the region coding for the first nucleotide binding fold. The RNA sequence between exons 10 and 13 was converted to cDNA and amplified by the polymerase chain reaction...

Topics

Alleles
Alternative Splicing
Base Sequence
Binding Sites
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
DNA
Female
Gene Expression Regulation
Humans
Male
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nucleotides

Polymerase Chain Reaction

RNA, Messenger

Source

Identifiers

PMID: 7684642
DOI: 10.1093/hmg/2.3.231

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7684642-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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