Article
Expression of CD45 isoforms in chronic B-cell leukaemias.
Leukemia research - 1 Mar 1993
Zola H, Siderius N, Flego L, Sparrow R, van der Weyden M B, Nimmo J, Hart D N, Houghton S, Boyd A W
Abstract excerpt
CD45 isoform expression was studied in 204 cases of B-cell lymphoproliferative disease, including 162 chronic lymphocytic leukaemia (CLL). In almost half the samples tested, CD45R0 was co-expressed with CD45RA, unlike normal B-cells, which express only CD45RA, except at terminal stages of differentiation. In a small number of cases CD45R0 was the dominant isoform expressed. No correlation could be discerned...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.